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Description

The control group showed epidermal disruption, mild reduction in dermal collagen fibers, new blood vessel formation, and minimal inflammatory cell infiltration

The addition of niacinamide to the formula soothes inflammation and reduces the visibility of enlarged openings of sebaceous glands, the so-called pores, and also prevents the formation of discoloration

4) Usually more substituted alpha-carbon of Michael donor is involved in the addition

VIC may also influence the production of cytokines, which are secreted by immune cells in infection and inflammation and are responsible for regulating both humoral and cellular immune responses, eliciting pro-inflammatory or anti-inflammatory responses