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[32], activation of this pathway suppresses pro-inflammatory cytokine production via NF-B inhibition and promotes the synthesis of prostaglandin D2, which in turn further attenuates NF-B signaling and associated inflammatory cascades [40]

The increased expression of apoptosis-related GADD45A was further reinforced by cleaved Caspase 3 in LH12 epithelium (Supplementary Fig

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While the precise mechanisms underlying the antioxidant and antiinflammatory effects of SGLT2 inhibitors remain unclear, studies have revealed the intricate molecular pathways involved in these processes [94, 97, 99]

Take one capsule daily or as recommended by the healthcare provider