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Caveolin-1 expression is essential for proper nonshivering thermogenesis in brown adipose tissue

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(PubMed) Lauer AA, Grimm HS, Apel B, et al

These successes are even more pronounced in those treated with tirzepatide, with nearly 60% of patients losing 20% of their weight and nearly 40% losing even more than 25% of their initial weight (Figure 6B)