glutathione free radical scavenger in hebrew JaypeeDigital Frontiers | Chemically Induced Models

Y.GoldbergA

It was also discovered that the levels of protein tyrosine kinase 2 (PTK2) were also suppressed in the curcumol-treated group of mice

As I mentioned in Article Breakdown Mechanisms of Pathogenesis in Drug Hepatotoxicity Putting the Stress on Mitochondria, I believe that this paragraph describes much of what occurs in floxed cells: Increased steady-state levels of mitochondrial superoxide, arising from reduction of Sod2 activity in the Sod+/mice (i.e., approximately half the wild-type activity), may be exacerbated by drugs that directly target the ETC [e.g., the complex I inhibitors flutamide and troglitazone (122)]

E.GroebnerJ

Yuan X, Yuan W, Ding L, Shi M, Luo L, Wan Y, Oh J, Zhou Y, Bian L, Deng DYB (2021) Cell-adaptable dynamic hydrogel reinforced with stem cells improves the functional repair of spinal cord injury by alleviating neuroinflammation