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Top Genes Interacting with Lead According to the CTD platform [77], lead interacts with 3448 genes, with the highest number of interactions reported for TNF (Tumor Necrosis Factor), CYP1A1 (Cytochrome P450 Family 1 Subfamily A Member 1), and CAT (Catalase), all of which are key players in inflammation and oxidative stress

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To address if selenate might be first reduced to selenite or selenide to trigger glutathione oxidation, we tested the impact of both Se species on the glutathione pool in the plastids of root cells

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