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This is done both for the overall and, because 12 of the warning letters were solely for registration deficiencies without appearing to have evaluated other potential deficiencies, with those 12 removed

Water-soluble allyl sulfones for dual site-specific labelling of proteins and cyclic peptides

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Similarly, other combination therapies targeting cancers deficient in FH and SDH are being explored and hold considerable promise [71, 151, 155, 156]

The oil-in-water method is suitable for water-soluble drugs, involving the dissolution of drugs and organic materials in the oil phase, followed by conversion to an aqueous phase through emulsification or ultrasound, resulting in the formation of nanoparticles with good dispersibility and stability 119