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However, apart from cross-linking its substrates, tTG can also hydrolyse peptide-bound glutamine to glutamic acid either at a lower pH or when no acceptor proteins are available, a process leading to an enhanced immunogenicity of gluten peptides [1,6] (Figure 1)

Gaosheng Zhou, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers