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Description

AO, antioxidant

RFC1 repeat expansion in Japanese patients with late-onset cerebellar ataxia

Following the initial weight loss, a second stage more definitive procedure was performed, but researchers found that most patients achieved significant weight loss within 12 months after surgery

Under this hypothesis, the increased signal is more likely to reflect non-G4 structural reorganization rather than G4 formation

Thus, our study adds to the growing body of evidence supporting the clinical translation of targeting LDHB alone or combined with radiotherapy and other ferroptosis-inducing therapies