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Kosmalski et al

doi: 10.1016/0014-5793(96)01027-7

Notably, XO activity is associated with obesity-related metabolic dysfunction, and XO inhibitors typically prescribed for gout or hyperuricemia are proving to be effective in mitigating cardiovascular and renal complications of diabetes (504, 507, 508)

GR was co-expressed with G6PD and GPX at protein level, which indicated that glutamine peroxidase and GSSH acted synergistically in glutamine synthesis pathway