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Congestive liver disease refers to a spectrum of liver abnormalities attributed to the passive congestion secondary to right-sided heart failure or any cause that increases the central venous pressure, including volume overload, severe pulmonary hypertension or valvulopathies.28 Elevated serum GGT or ALP are characteristic biochemical abnormalities in CKD patients with left ventricular diastolic dysfunction, especially if they are associated with pulmonary congestion,29 which is also a recognised risk factor for mortality in these patients.30 Elevated GGT can also reflect microsomal enzyme induction.31 In addition to alcohol intake, many drugs can induce liver enzymes

With lipoproteinemia, lipoprotein ingestion is excessive, and the RPE becomes cholesterol-overloaded

The data also show that cellular thiol concentrations were augmented in the presence of GSH and NAC and these compounds were cytoprotective against HgCl 2 and this is due to up regulating of GSH synthesis

10.1038/nm1233 175 Skrzyska-DziduszkoK

Souhaitons que cette explication rduise en partie la confusion, plutt que den crer davantage