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This increase was significantly abolished when BSO and DEM were combined with erastin (Supplemental Fig

Glutathione supplementation improves oxidative damage in experimental colitis

MAPKs, including extracellular signal-regulated kinases (ERK), c-Jun N-terminal kinases (JNK), and p38 MAPKs, regulate various cellular activities such as growth, differentiation, and apoptosis

We always include plenty of hydration fluids because proper hydration is crucial for eliminating the toxins that glutathione has neutralized

The authors hypothesised that xCT inhibition might be further potentiated by limiting glutamate or glutamine availability, and show that xCT is a compelling therapeutic target for triple-negative tumours