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The lumbar region (vertebrae L1-L5) features vertebrae that are much larger to absorb the stress of lifting and carrying heavy objects

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Furthermore, by targeting and eliminating senescent cells, which accumulate with age and contribute to inflammation and tissue dysfunction, FOXO4-DRI could help improve cardiac health for those suffering with heart disease

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By attaching a larger molecule, like a polyethylene glycol (PEG) chain (a process called PEGylation), scientists can make the peptide too large to be easily filtered by the kidneys and can also sterically hinder the approach of degrading enzymes