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Additionally, TPO-Ab enhance pro-inflammatory cytokine responses to TPO in mononuclear cells (49).Ott et al., demonstrated that elevated pre-operative TPO-Ab levels were significantly associated with fatigue, irritability, and reduced QoL in euthyroid patients undergoing surgery for benign goitre (47)

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(6) However, some people may never have thyroid antibodies present in blood but sure enough, upon a thyroid ultrasound or biopsy, changes in the gland that are consistent with Hashimotos, will be apparent

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Symptoms of Stevens-Johnson syndrome Stevens-Johnson syndrome can start with flu-like symptoms, such as a high temperature, sore throat, cough and joint pain