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doi: 10.1016/j.immuni.2006.03.011 159 KawabuchiMSatomiYTakaoTShimonishiYNadaSNagaiKet al

doi: 10.1111/bjh.12266 93 OudaertIvan der VrekenAMaesADe BruyneEDe VeirmanKVanderkerkenKet al

Notably, NAD + levels were not determined in this study 330

This heterogeneity encompasses genetic, phenotypic and microenvironmental variations among cancer cells, resulting in subpopulations with varying treatment sensitivities [386]

Adenine and PRPP synthesis is catalyzed by AMP and PPi under the action of adenine phosphoribosyltransferase (APRT), facilitated by a divalent Mg 2+ ion (Huyet et al., 2018)