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The injection site reactions are more prominent than GLP-1s but not treatment-limiting for most people

10.1016/j.bbrc.2016.10.031 Biochem

However, if food is stored or precooked for a long time, more histamine can be formed by heating and storing, so that a meal that was tolerated the day before can cause discomfort the next day

GLP-1 medications can cause GI side effects

The slow diffusion of SERF2 in TERRA12 rG4 condensates may be due to strong electrostatic interactions of charged lysine and arginine residues with negatively charged nucleic acid bases, as has been observed for other nucleic acid-binding proteins 90