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August D, Janghorbani M, Young VR

In addition, inhibiting complexes III or IV in these cells can cause the generation of various pro-inflammatory stimuli such as cytokines IL-1, IL-6 , and IL-18 , prostaglandin e2 (PGe2), chemokines IL-8 and monocyte chemotactic protein 1, and proteases MMP1 , MMP3 , and MMP13 (120)

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c , HeLa cells were untreated or treated with Camptothecin (CPT, 1 M, 30 min, left) or 5-Aza-2-deoxycytidine (5-aza-dc, 100 M, 30 min, right) as indicated