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Mitochondria-targeted antioxidant SS-31 is a potential novel ophthalmic medication for neuroprotection in glaucoma

Etnyre D, Stone AL, Fong JT, Jacobs RJ, Uppada SB, Botting GM, Rajanna S, Moravec DN, Shambannagari MR, Crees Z, et al

Some patients see modest improvements in muscle density during treatment

In conclusion, this shows that only the strongly coordinating side chains from histidine and cysteine lead to ROS production, and for efficient ROS production copper has to be coordinated by at least two side chains