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10.1016/j.tox.2010.10.011 Toxicology 105 LuetjensC

Epub 2007 Oct 19

Pyruvate is metabolized to lactate in the cytosol or converted to acetyl coenzyme A (acetyl-CoA) in the mitochondria to fuel the tricarboxylic acid (TCA) cycle, enhance OXPHOS, and generate ATP [18,19]

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