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Use only under medical supervision, particularly prior to surgery, to reduce risks

Hedya, Potential cardioprotective and anticancer effects of carvedilol either free or as loaded nanoparticles with or without doxorubicin in solid Ehrlich carcinoma-bearing mice

Bilateral retinal detachment Retinal detachment is an emergency medical condition that requires prompt treatment, leading to permanent blindness

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Berberine side effects are predominantly gastrointestinal and may include: Diarrhoea, constipation, or abdominal discomfort Nausea and flatulence Cramping or bloating These effects are typically dose-dependent and may be minimised by starting with lower doses and taking berberine with meals