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10.1080/07391102.2020.1761881 28 EvirgenO.GkeA.OzturkO

In addition, combretastatin disrupts the endothelial cell junction molecule (VE-cadherin) leading to vascular collapse [45] and in vivo studies show that combretastatin is able to reduce immature vessels [45, 46]

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Similarly, CPT improved motor function and reduced neuronal loss in LPS-induced PD models by balancing microglial polarization via the AKT/Nrf2/HO-1 and NF-B pathways, further underscoring the importance of microglial phenotype regulation in neuroprotection (He et al., 2021)

The study continues to assess hair growth, density, shedding and overall hair quality