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In hypoxic-ischemic brain damage, glycyrrhizin (GL), an HMGB1 inhibitor, can suppress the RSL3- or oxygen-glucose-deprivation-induced neuronal ferroptosis via the HMGB1/GPX4 pathway [167]

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A randomized, double-blind trial published in the European Journal of Nutrition found that daily oral glutathione at 1,000mg over six months increased glutathione levels by 30 to 35% in erythrocytes, plasma, and lymphocytes among 54 adults

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