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Based on this the use of phosphate buffer, pH 7.4, was suggested by Silk et al to reduce the undesirable non-enzymic hydrolysis to negligible proportions despite of a pH optimum of 8.5 26

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Srensen KK, Simon-Santamaria J, McCuskey RS, Smedsrd B

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DOI: Received: Accepted: Published: Publisher Name: Springer, Cham Print ISBN: 978-3-030-81404-5 Online ISBN: 978-3-030-81404-5 eBook Packages: Living Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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This type of histological evidence is absent from Matrixyls published record

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[,] DPA is suited for both oral and intravenous chelation treatment

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