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7 Park SA, Byeon G, Jhoo JH, Kim HC, Lim MN, Jang JW, Bae JB, Han JW, Kim TH, Kwak KP, Kim BJ, Kim SG, Kim JL, Moon SW, Park JH, Ryu SH, Youn JC, Lee DW, Lee SB, Lee JJ, Lee DY, Kim KW

Supplementary material The Supplementary Material for this article can be found online at: Footnotes References 1 AhmadL.RylottE

Statistics and reproducibility For analysis of differentially expressed genes (transcriptome) we refer to the specific sections above

Moreover, we assessed CoQ10 content and NAD + /NADH ratios, which are closely associated with FSP1s anti-ferroptotic function, PPARa over-expression not only increased FSP1 levels but also enhanced CoQ10 activity and elevated NADH content (Fig