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In addition, several enzymes engaged in mitochondrial respiration are found to regulate ferroptotic cell death, such as SCO2 and fumarate hydrase (FH)[44, 116]

Notably, each round of this reduction (to sulfide) consumes two ATP molecules, as well as reducing equivalents from four NADPH molecules [details reviewed in (Thomas and Surdin-Kerjan, 1997)]

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Randomized trial of the triple monoamine reuptake inhibitor NS 2330 (tesofensine) in early Parkinson''s disease