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Although the mechanisms whereby TNBS cause an inflammatory response are not completely defined, this response is thought to be initiated by macrophage-mediated recognition and degradation of the TNBS-modified cells and proteins within the colonic interstitium (Grisham et al, 1991

References The Permanente journal , 26 (2), 8997

Ben J, Zhang Y, Zhou R, Zhang H, Zhu X, Li X, Zhang H, Li N, Zhou X, Bai H, Yang Q, Li D, Xu Y, Chen Q

Antifungal Medications Antifungal medication itraconazole is associated with reports of cardiotoxicity, hypertension, ventricular fibrillation, ventricular contractions, worsening of existing heart failure, and increasing the risk for new-onset heart failure

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