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2 Materials and methods 2.1 Chemicals SkQ1 and dodecyltriphenylphosphonium bromide (C 12 TPP) were kindly provided by the Institute of Mitoengineering, Lomonosov Moscow State University

Here we have used a specific panel of antibodies chosen on the basis of their involvement in DNA repair, oxidative stress, cell cycle dynamics, senescence and apoptosis to investigate potential markers of canities within hair bulb melanocytes in the scalp of multiple normal healthy donors aged from 22 to 70 years old

qtot 0.414 47 HGA2 1 ful H47 47 0.09 1.008

Furthermore, ATF2 forms heterodimers with HDAC1 to induce Socs-3 transcription to negatively regulate TLR4-mediated inflammation (118), demonstrating its dual regulatory nature