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This pathway reduces appetite through central nervous system signaling, slows gastric emptying to promote satiety, and improves insulin sensitivity

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168,169 Lactate-derived lactylation, found throughout the brain, influences chromatin state and gene expression (Fig

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Crees research has also focused on the transition of care for these patients, making it easier for them to seamlessly grow into adult care without compromising the multidisciplinary care they received as children