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Role of quinones in toxicology

A neuropsychological and quantified EEG study

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By contrast, ATF7 contributes to innate immune memory by modulating STAT1/NF-B-dependent inflammatory networks (such as CXCL9/10), thus enhancing macrophage-mediated responses against bacteria and fungi (119)

However, like previous studies, researchers attributed the cytotoxicity of elesclomol to the excessive production of ROS and could not explain why the cell death induced by elesclomol was closely related to mitochondrial respiration and why the sensitivity of cells with active mitochondrial respiration to elesclomol was nearly 1000 times higher than that of cells with active glycolysis