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3.2.3 Hesperidin and hesperetin Hesperidin (HSD) is a subgroup of citrus flavonoids, primarily extracted from bitter orange peel powder (146)

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After evaporation of the solvents, flash chromatography was performed and the following preparative reversed-phase HPLC separation allowed to obtain APAP-CYS in yield of 21% after two reaction steps

doi: 10.1016/j.mce.2023.111913 155 MaoHWangLXiongYJiangGLiuX