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Description

Interaction between c-Abl and Arg tyrosine kinases and proteasome subunit PSMA7 regulates proteasome degradation

For instance, WSG has been shown to facilitate the degradation of EGFR, TGFRI and TGFRII via proteasomal pathways, resulting in a significant reduction in metastatic lung nodules and prolonged survival in LLC-bearing mice [32]