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This action reduces the activation of the apoptosis pathway induced by IR, subsequently downregulating the expression levels of cytochrome c oxidase subunit 4 (Cox-4), Bax, and cleaved caspase-3, while also decreasing the secretion of TNF-, IL-1, and IL-6 (Ling et al., 2024).Quercetin 3-rutinoside (Q-3-R) is primarily found in buckwheat, citrus fruit peels, and apples, and exhibits biological activities, including antioxidant and anti-inflammatory effects

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Supporting it doesnt mean drastic cleanses or complicated diets

As to the difference between the two, Wedgwood says its all about the roles they play in the body