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10.1038/jp.2017.74 9

Simultaneously, angiogenesis-related factors induce macrophage polarization toward the M2 phenotype, thereby leading to the development of an immunosuppressive tumor microenvironment (TME)

These findings support the further investigation of glutamine-coupled organophilin (IV) compounds as potential chemotherapeutic agents for the treatment of colon cancer [186]

Responsively Degradable Nanoarmor-Assisted Super Resistance and Stable Colonization of Probiotics for Enhanced Inflammation-Targeted Delivery

40 Sympathetic dominance (ie, excessive fight-or-flight activation relative to resting nervous system activity) and the inability to mount a normal adaptive response to stress promote multiple symptoms, including pain, cognitive dysfunction, and feelings of stress