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In vitro reactivation of the FMR1 gene involved in fragile X syndrome

Chen et al developed BTO@DPA nanoparticles by coating BTO with amphiphilic polyarginine (DPA) ( Citation77 The study found that BTO@DPA nanoparticles could efficiently generate NO under US irradiation, which reacted with ROS to form more effective peroxynitrite (ONOO ), causing severe apoptosis in tumor cells under both hypoxic and normoxic conditions

[DOI] [PubMed] [Google Scholar] 52.Freed GL, Clark SJ, Butchart AT, Singer DC, Davis MM

Others can take 5-30 minutes

Additionally, it addresses redness associated with conditions like acne and rosacea, while promoting mild anti-aging effects through improved skin texture and collagen production