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MMP9 was also elevated significantly in blood samples from acute aortic dissection (AAD) patients, and the incidence of AAD was reduced significantly, by 40%, following the administration of an MMP inhibitor and was almost completely blocked in Mmp9 / mice [44]

Oxidative stress and antioxidants for idiopathic oligoasthenoteratospermia: Is it justified

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The work reported herein confirms synergy in the U373-V (TMZ-sensitive) cell line, and in the two cell lines harbouring clinical resistance mechanisms to TMZ for the first time

1.2.2 Pharmacodynamics Single pharmacodynamic aspects, allowing detailed determination of specific cellular responses, can be studied in detail in cell cultures