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Curcumin induced CYP3A4 in multiple models, including HepG2 cells ( Curcumin may reduce CYP19A1 expression levels by suppressing ERR, a mechanism independent of ATZ As previously mentioned, CYP19A1 plays a critical role in the last step of estradiol biosynthesis

3 Neurogenic inflammation in migraine Neurogenic inflammation is defined as an acute sterile inflammation triggered by the release of neuropeptides from peripheral nociceptive fibers, leading to plasma protein extravasation and vasodilation (10)

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Substituted amphetamines, which are also called phenylpropylamino alkaloids, are a diverse group of nitrogen-containing compounds that feature a phenethylamine backbone with a methyl group at the -position relative to the nitrogen (Figure 1)

Moreover, clinical chemistry parameters of hamsters treated with LSC-Exo remained within the normal ranges (Fig