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It is investigated in experimental models for its interaction with growth factor signaling, angiogenesis-related mechanisms, and cytoprotective process

Manufacturing is simpler, and there are fewer drug-drug interaction concerns because there is only one drug

Therefore, the authors hypothesized that the beneficial effect exerted by BMSCs in the nervous system might depend on HGF secretion and on HGF-MET axis activation (Zheng et al., 2013