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Retinoic Acid and Retinoic Acid Receptors as Pleiotropic Modulators of the Immune System

Given the importance of Complex I in the OxPhos pathway, any mutation that affects its function could gravely perturb the ETC, resulting in decreased ATP synthesis and increased production of ROS and other reactive species

These chemokines recruit neutrophils and tumor-associated macrophages, reshaping the immune microenvironment to promote tumor progression [114]

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Crosstalk between HSPA5 arginylation and sequential ubiquitination leads to AKT degradation through autophagy flux