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As a cytoprotective agent, mediating Roberts cytoprotection, it maintains endothelium integrity and has a particular angiomodulatory effect (Sikiric et al., 1993

Galluzzi, L

A major advancement in this area is Emispheres Eligen technology, which employs sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC) as a permeation enhancer to facilitate the oral bioavailability of peptide-based drugs

Vertical bands involving underlying muscle (platysmal bands) respond less to topical treatment but may still show some improvement in overlying skin texture

To address this gap, we propose the concept of a Dynamic Living Digital Twin framework for precision dosing in critical illness