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For example, a dose of 20 mg/kg Gouqizi polysaccharides reduced testicular spermatogenic damage in mice and regulated the expression of GPX4 and AIF (Liu et al., 2021), while a lower dose of 10 mg/kg improved the sperm quality, the expression of TNP2 and RPL31, and the apoptosis of germ cells (Liu C

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8,9 Manifestations Vitamin B 12 deficiency affects multiple systems, and sequelae vary in severity from mild fatigue to severe neurologic impairment 1,2,6,10 (Table 2 4,10 )

[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Yip L., Dart R