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Results Metformin alleviated OA pain in MIA-induced mouse model Firstly, an OA model was established by injecting MIA into the knee joints cavity of 6-month-old male C57 WT mice

Dorland's Illustrated Medical Dictionary 32nd edn (Elsevier Health Sciences, 2011)

Mechanisms of TDP-43 proteinopathy onset and propagation

Concentrations and routes referenced below are drawn from peer-reviewed preclinical literature on each peptide individually

These animals produced low systemic levels of NO at 12 h of infection compared to saline-CLP group, increasing this production at 24 h post infection (Figure 2H)