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Until other studies are done, Miller recommends those who are co-prescribed to these drugs to observe vitamin B 12 status and take vitamin B 12 supplements if needed [93]

doi:10.1080/09593985.2016.1194646

Elevated levels of certain compounds may indicate dysbiosis and increased metabolic stress, which can indirectly affect neurotransmitter balance, mitochondrial function, and neuroinflammatory pathways

Regarding the results of all of these studies, they found a dose-response relationship between serum homocysteine and the odds ratio of ischemic heart disease, supporting the idea that homocysteine is a causal risk factor for cardiovascular disease

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