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doi: 10.1016/j.msec.2019.04.064 152 YeoIL

Rather, it works by restoring the biological signaling that illness, inflammation, and cellular dysfunction have disruptedwhich is precisely the goal in long COVID recovery

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These cells accumulate with age and release harmful substances that cause chronic inflammation and tissue damage

68 Similarly, the link between PD and the braingutmicrobiome axis is hotly debated: the gutfirst hypothesis proposes that gut microbial dysbiosis may trigger neurodegeneration via the vagus nerve or immune system, which is quite compelling, whereas interestingly, the brainfirst hypothesis suggests that brain pathology (e.g., -synuclein aggregation) may occur first and affect the gut microbiota