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To overcome this instability and improve systemic delivery, several formulation strategies have been explored

These microorganisms will have developed mechanisms to survive the various defensive mechanisms produced by the host such as antimicrobial peptides

Given that critical protective and detoxifying role, it is not surprising that more than 25% of the bodys glutathione is found in the liver with high levels also present in the kidneys, lungs, adrenal glands, reproductive organs, brain and pancreas