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Smoking has emerged as an independent pathogenic contributor to RA [35]

80,81 They neutralize ROS, modulate antioxidant-enzyme activity, and regenerate other antioxidants

This observation prompted our investigation into the role of cellular metabolic status, with particular emphasis on oxidative stress during human endoderm specification

To assess muscle damage by Evans blue dye incorporation, a 1% Evans blue dye (Sigma-Aldrich) solution (in 0.9% NaCl and sterile filtered) was administered intraperitoneally (i.p.) 16 h before the dissection at a dosage of 1% volume per gram of the mouses body weight

Urticaria, or hives, is characterized by red, itchy welts on the skin