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Chloramphenicol (Chloromycetin): metabolized by cytochrome P450 to an alkylating metabolite that inactivates cytochrome P450 Other inactivators: Mechanism of Action: -- targeting the heme moiety: Steroids: Ethinyl estradiol (Estinyl) Norethindrone (Aygestin) Spironolactone (Aldactone) Others: Propylthiouracil Ethchlorvynol (Placidyl) Overview: Phase II reactions involve non-microsomal enzymes Reaction types: Conjugation Hydrolysis Oxidation Reduction Location (non-microsomal enzymes): primarily hepatic (liver)

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Clinical Update 5/22/2021 Possible Toxin in Straws Potentially toxic compounds known as PFAS occur in some brands of dental floss and a variety of other products

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9th Annual Oncology Update: Advances & Controversies

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Therapeutic effects of human umbilical cord mesenchymal stem cell-derived microvesicles on premature ovarian insufficiency in mice

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evaluated the prognostic significance of elevated plasma CRP levels in 261 prostate cancer patients undergoing radiotherapy

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