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Three complementary signal detection approaches were applied to enhance robustness and reduce the risk of false-positive findings [ Subgroup analyses in pregnancy and autoimmune indications To further explore population-specific safety signals, subgroup analyses were performed in pregnant women and in patients with autoimmune diseases commonly treated with AZA

Intravenous acetylcysteine has the advantage of shortening hospital stay, increasing both doctor and patient convenience, and it allows administration of activated carbon to reduce absorption of both the paracetamol and any co-ingested drugs without concerns about interference with oral acetylcysteine.[49] Baseline laboratory studies include bilirubin, AST, ALT, and prothrombin time (with INR)