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This effect of MT-1G is achieved by blocking the GSH depletion-mediated lipid peroxidation to inhibit ferroptosis in HCC cells, independent of iron ion content

According to research studies, lipoate, a conjugate base of ALA takes part in several oxidative metabolic processes where it is reduced to dihydrolipoate under physiological conditions

FIGURE 3 3.7.2 PANoptosis and ferroptosis Recently, studies have demonstrated that pyroptosis, apoptosis, and necroptosis (PANoptosis) have taken place in MCAO rats (Yan et al., 2022)