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The MAPK pathway, including ERK, JNK and p38 kinase, plays a pivotal role in cell survival, proliferation and migration of tumor cells [7,8,9]

These enzymes eliminate the effects of superoxide radicals and protect the cells against the harmful effects of these radicals

That selectivity is what makes AOD-9604 unique in the peptide space

Five transcripts out of 8 were aligned along this genome overlapping glutathione S-transferase annotated loci , revealing the still incomplete nature of the C

After a further 24 h, the cells were washed with cold PBS, lysed by sonication (4 C, 5 min), and centrifuged at 10,000 g for 10 min