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[,] However, in persons already suffering from mercury or lead toxicity, the half-life of DMSA may be longer

In addition, the enhanced expression and activity of HO-1 by glutathione was associated with an increase in the total protein expression of Nrf2 and its phosphorylation at serine 40 (p-Nrf2), whereas the expression of Keap1, a negative regulator of Nrf2, was reduced in a glutathione treatment concentration-dependent manner (Figure 3A)

Nevertheless, due to continuous emission and accumulation, both organic and inorganic As have been reported in higher concentration from aquatic environments compared to terrestrial environments (IPCS 2001)

Proponents of this view suggest that neuronal energy demands during activation are met directly by glucose or other mechanisms, minimizing the quantitative importance of an intercellular lactate shuttle (Dienel, 2012, 2017)

doi: 10.1515/cclm-2012-0689 262