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Cell-mediated immunity plays a central role, with nave CD4 + T cells differentiating into effector subsets upon antigen recognition: Th1 cells secrete IFN-, IL-2, and TNF-, inducing MHC class II expression and promoting Fas-mediated apoptosis of thyrocytes

tablet formulation in patients with mild-to-moderately-active ulcerative colitis: a multicenter, randomized, double-blind, placebo-controlled study

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